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Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males.成年男性肾小球滤过率、有效肾血浆流量和肾小管排泄能力的年龄变化。
J Clin Invest. 1950 May;29(5):496-507. doi: 10.1172/JCI102286.
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Adverse drug events in hospitalized elderly.住院老年人的药物不良事件
J Gerontol A Biol Sci Med Sci. 1998 Jan;53(1):M59-63. doi: 10.1093/gerona/53a.1.m59.
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Fluid and electrolyte homeostasis in the elderly: physiological changes of ageing and clinical consequences.
Baillieres Clin Endocrinol Metab. 1997 Jul;11(2):367-87. doi: 10.1016/s0950-351x(97)80347-3.
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Drug-related problems in elderly patients admitted to Tayside hospitals, methods for prevention and subsequent reassessment.泰赛德地区医院收治老年患者的药物相关问题、预防方法及后续重新评估
Age Ageing. 1997 Sep;26(5):375-82. doi: 10.1093/ageing/26.5.375.
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Renal haemodynamics in the elderly.
Nephrol Dial Transplant. 1996;11 Suppl 9:2-8. doi: 10.1093/ndt/11.supp9.2.
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The association of age and frailty with the pharmacokinetics and pharmacodynamics of metoclopramide.年龄和虚弱与胃复安的药代动力学和药效学的关联。
Age Ageing. 1993 Sep;22(5):354-9. doi: 10.1093/ageing/22.5.354.
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Age-related changes in beta-adrenergic neuroeffector systems in the human heart.人类心脏中β-肾上腺素能神经效应系统的年龄相关变化。
Circulation. 1994 Sep;90(3):1225-38. doi: 10.1161/01.cir.90.3.1225.
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Review: the frequency and severity of adverse drug reactions in elderly people.
Age Ageing. 1994 May;23(3):255-9. doi: 10.1093/ageing/23.3.255.
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Prescribing in the elderly.老年人用药处方
Postgrad Med J. 1995 Aug;71(838):466-71. doi: 10.1136/pgmj.71.838.466.
10
Adverse reactions to prescribed drugs in the elderly: a multicentre investigation.老年人处方药不良反应：一项多中心调查。
Age Ageing. 1980 May;9(2):73-80. doi: 10.1093/ageing/9.2.73.

Prescribing for the elderly patient: why do we need to exercise caution?

作者信息

Hughes S G

机构信息

Division of Geriatrics, St George's Hospital Medical School, London.

出版信息

Br J Clin Pharmacol. 1998 Dec;46(6):531-3. doi: 10.1046/j.1365-2125.1998.00842.x.

DOI:10.1046/j.1365-2125.1998.00842.x
PMID:9862240
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1873806/
Abstract
摘要