Mueller M J
Institute of Pharmacy, University of Munich, Karlstrasse 29 D-80333, Munich, Germany.
Chem Biol. 1998 Dec;5(12):R323-33. doi: 10.1016/s1074-5521(98)90660-3.
Animal prostaglandins and plant jasmonates are well-known enzymatically formed cyclopentanoic lipids that have regulatory functions and serve as inducible mediators of host defense reactions. A novel group of prostaglandin-like compounds, the isoprostanes, generated in animals and plants by a nonenzymatic, free radical-catalyzed process, are now suspected to be mediators of oxidant injury in vivo.
动物前列腺素和植物茉莉酸酯是众所周知的通过酶促形成的环戊烷类脂质，它们具有调节功能，并作为宿主防御反应的诱导性介质。现在怀疑，动物和植物中通过非酶促自由基催化过程产生的一类新型前列腺素样化合物——异前列腺素，是体内氧化损伤的介质。
