Wauschkuhn B, Verleger R, Wascher E, Klostermann W, Burk M, Heide W, Kömpf D
Medical University of Lübeck, Department of Neurology, 23538 Lübeck, Germany.
J Neurophysiol. 1998 Dec;80(6):2900-10. doi: 10.1152/jn.1998.80.6.2900.
Lateralized human cortical activity for shifting visuospatial attention and initiating saccades. J. Neurophysiol. 80: 2900-2910, 1998. The relation between shifts of visual attention and saccade preparation was investigated by studying their electrophysiological correlates in human scalp-recorded electroencephalogram (EEG). Participants had to make saccades either to a saliently colored or to a gray circle, simultaneously presented in opposite visual hemifields, under different task instructions. EEG was measured within the short interval between stimulus onset and saccade, focusing on lateralized activity, contralateral either to the side of the relevant stimulus or to the direction of the saccade. Three components of lateralization were found: 1) activity contralateral to the relevant stimulus irrespective of saccade direction, peaking 250 ms after stimulus onset, largest above lateral parietal sites, 2) activity contralateral to the relevant stimulus if the stimulus was also the target of the saccade, largest 330-480 ms after stimulus onset, widespread over the scalp but with a focus again above lateral parietal sites, and 3) activity contralateral to saccade direction, beginning about 100 ms before the saccade, largest above mesial parietal sites, with some task-dependent fronto-central contribution. Because of their sensitivity to task variables, component 1 is interpreted as the shifting of attention to the relevant stimulus, component 2 is interpreted as reflecting the enhancement of the attentional shift if the relevant stimulus is also the saccade target, and component 3 is interpreted as the triggering signal for saccade execution. Thus human neurophysiological data provided evidence both for independent and interdependent processes of saccade preparation and shifts of visual attention.
用于转移视觉空间注意力和引发眼跳的人类大脑皮层活动的偏侧化。《神经生理学杂志》80: 2900 - 2910, 1998年。通过研究视觉注意力转移和眼跳准备在人类头皮记录脑电图（EEG）中的电生理相关性，对它们之间的关系进行了研究。参与者必须在不同的任务指令下，对同时呈现在相对视觉半视野中的显著彩色圆圈或灰色圆圈进行眼跳。在刺激开始到眼跳的短时间间隔内测量EEG，重点关注偏侧化活动，其与相关刺激的一侧或眼跳方向对侧。发现了三种偏侧化成分：1）与相关刺激对侧的活动，与眼跳方向无关，在刺激开始后250毫秒达到峰值，在外侧顶叶部位上方最大；2）如果刺激也是眼跳目标，则与相关刺激对侧的活动，在刺激开始后330 - 480毫秒最大，在头皮上广泛分布，但再次聚焦于外侧顶叶部位上方；3）与眼跳方向对侧的活动，在眼跳前约100毫秒开始，在内侧顶叶部位上方最大，有一些与任务相关的额中央贡献。由于它们对任务变量敏感，成分1被解释为对相关刺激的注意力转移，成分2被解释为反映如果相关刺激也是眼跳目标时注意力转移的增强，成分3被解释为眼跳执行的触发信号。因此，人类神经生理学数据为眼跳准备和视觉注意力转移的独立和相互依存过程提供了证据。
