Lange W, Köhler H, Apodaca J
Dtsch Med Wochenschr. 1976 Aug 27;101(35):1273-6. doi: 10.1055/s-0028-1104255.
The Hepatest, a passive haemagglutination test, proved to be, like other tests of this group, significantly more sensitive for routine examination of hepatitis B(surface) antigen than tests of the first and second generation, but was not as sensitive as the Ausria II 125 test. The lowest HBs antigen concentration demonstrable in the Hepatest was 31 ng/ml for the subtype ad and 47 ng/ml for subtype ay (in the Ausria II 125 test lowest concentrations were 1.0 and 1.5 ng/ml, respectively). There were several false-positive reactions in the specificity test. Thus all positive reactions would need to be checked, more often than with the Ausria test. But the Hepatest proved to be the most practicable of all the third generation tests, both with regard to shortness of reaction time, technical requirements and ease of reading off the results.
“肝炎检测”（一种被动血凝试验）结果表明，与该组中的其他检测一样，对于乙肝（表面）抗原的常规检测，它比第一代和第二代检测显著更灵敏，但不如澳抗II 125检测灵敏。“肝炎检测”中可检测到的乙肝表面抗原最低浓度，对于ad亚型为31纳克/毫升，对于ay亚型为47纳克/毫升（在澳抗II 125检测中，最低浓度分别为1.0和1.5纳克/毫升）。在特异性检测中有几例假阳性反应。因此，所有阳性反应都需要进行核查，比使用澳抗检测更频繁。但“肝炎检测”在所有第三代检测中被证明是最实用的，在反应时间短、技术要求和结果判读简便性方面均如此。
