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常规医院实践中用于检测乙型肝炎表面抗原的被动血凝方法的比较研究。

A comparative study of passive haemagglutination methods for the detection of hepatitis B surface antigen in routine hospital practice.

作者信息

Withers M J, McCahill G V, Griffiths P D, Heath R B, Pattison J R, Dane D S

出版信息

J Clin Pathol. 1976 Aug;29(8):732-5. doi: 10.1136/jcp.29.8.732.

Abstract

Two passive haemagglutination methods for detecting HBsAg were compared. In general, the method using turkey erythrocytes was found preferable to the method employing sheep cells since it is more rapid and more sensitive, and less frequently gave rise to false positive reactions with sera from staff, blood donors, and patients not receiving haemodialysis. The turkey cell test gives rise to more false positive screen tests than the sheep cell test when monitoring renal dialysis patients since approximately 10% of the sera of these patients were found to contain turkey cell agglutinins, but this presents no particular difficulty if the recommended absorption procedures are used.

摘要

对两种检测乙型肝炎表面抗原(HBsAg)的被动血凝方法进行了比较。总体而言,发现使用火鸡红细胞的方法优于使用绵羊细胞的方法,因为它更快、更灵敏,并且与工作人员、献血者和未接受血液透析患者的血清产生假阳性反应的频率更低。在监测肾透析患者时,火鸡细胞检测比绵羊细胞检测产生更多的假阳性筛查结果,因为发现这些患者中约10%的血清含有火鸡细胞凝集素,但如果使用推荐的吸收程序,这不会带来特别的困难。

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Which techniques should be used to screen blood donations for hepatitis B surface antigen?
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