Yue G P, Chen Q, Dai N
Institute of Acupuncture and Meridians, Anhui College of TCM, Hefei.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 May;17(5):289-91.
To explore the therapeutical mechanism of Bushen Shengjing Decoction (BSSJD) in treating infertility.
Fed Wistar male rats with adenine 30 mg/100 g.d continuously for 30 days. The rats manifested the symptom which was similar to the human Kidney Yang Deficiency, the genitality dropped, the function of sperm-producing in the testis was disturbed, the contents of luteinizing hormone (LH), testosterone (T) and compound F (F) in blood were all lower than rats of normal group, P < 0.01. The model rats took the BSSJD 3 ml/100 g.d (each ml contains crude drugs 2 g) continuously for 10 days, interval for three days, then medicated again and total medication of BSSJD was 30 days.
The symptom of Kidney Yang Deficiency in rats was improved obviously, the genitality, sperm quality and function of sperm producing in testis were all enhanced obviously, so did the hormone level of LH, T, F in blood. Comparing to untreated control group, the difference was significant (P < 0.05).
BSSJD has the function of reinforcing Yang and replenishing essence and regulate the endocrinological function.
探讨补肾生精汤治疗不孕症的作用机制。
以30mg/100g.d的腺嘌呤连续喂养Wistar雄性大鼠30天。大鼠出现类似于人类肾阳虚的症状，生殖能力下降，睾丸生精功能紊乱，血液中黄体生成素（LH）、睾酮（T）和复合F（F）的含量均低于正常组大鼠，P<0.01。模型大鼠以3ml/100g.d的补肾生精汤（每毫升含生药2g）连续给药10天，间隔3天，然后再次给药，补肾生精汤总给药时间为30天。
大鼠肾阳虚症状明显改善，生殖能力、精子质量及睾丸生精功能均明显增强，血液中LH、T、F激素水平也明显升高。与未治疗的对照组相比，差异有统计学意义（P<0.05）。
补肾生精汤具有壮阳填精作用，可调节内分泌功能。
