Bosković V, Opalić J, Petković S, Ostojić N, Radosavljević A
Institute of Gynaecology and Obstetrics, Clinical Centre of Serbia, Belgrade.
Srp Arh Celok Lek. 1998 May-Jun;126(5-6):188-91.
Primary malignant tumours of the Fallopian tube are among the rarest of gynaecological malignancies. Seven patients with primary malignant tumour of the Fallopian tube, treated between 1991 and 1996, were studied. The average age was 60 years, with nulliparity rate of 29 percent and a mean parity of 2.2. The most common symptoms were atypical vaginal bleeding (29 percent), abdominal pain and distention (29 percent), whereas 43 percent of patients had no symptoms. No patient had a correct preoperative diagnosis. Primary surgical treatment was in all patients hysterectomy and bilateral salpingo-oophorotomy with or without omentectomy. Staging was done according to the FIGO classification for Fallopian tube carcinomas. In Stage I 29 percent of patients were classified, 43 percent in Stage II and 29 percent in Stage III. Six patients (86 percent) had adenocarcinoma (1 in G1, 2 in G2, 3 in G3) and 1 had MMMT (malignant mixed tumour-heterology type). All patients received additional postoperative therapy including: chemotherapy (58 percent), radiotherapy (14 percent), hormonotherapy (14 percent) or combination of chemotherapy and hormone therapy (14 percent). Our results are comparable to those of other authors. The time is too short to predict a 5-year survival, but this will be reported in our next paper.
原发性输卵管恶性肿瘤是妇科恶性肿瘤中最为罕见的类型之一。我们对1991年至1996年间接受治疗的7例原发性输卵管恶性肿瘤患者进行了研究。患者平均年龄为60岁，未生育率为29%，平均产次为2.2。最常见的症状为非典型阴道出血（29%）、腹痛和腹胀（29%），而43%的患者无症状。术前均未做出正确诊断。所有患者均接受了原发性手术治疗，即子宫切除术及双侧输卵管卵巢切除术，部分患者还进行了大网膜切除术。根据国际妇产科联盟（FIGO）输卵管癌分期标准进行分期。I期患者占29%，II期占43%，III期占29%。6例患者（86%）为腺癌（G1级1例，G2级2例，G3级3例），1例为恶性混合苗勒管肿瘤（异源性）。所有患者术后均接受了辅助治疗，包括化疗（58%）、放疗（14%）、激素治疗（14%）或化疗与激素治疗联合应用（14%）。我们的结果与其他作者的结果相当。目前观察时间较短，尚无法预测5年生存率，但我们将在下一篇论文中予以报道。
