[药物对白细胞迁移的影响]
[Effects of drugs on leukocyte migration].
作者信息
Mukaide A, Kameyama T
出版信息
Nihon Yakurigaku Zasshi. 1976;72(1):59-61.
PMID:986350
Abstract
The effects of various drugs on chemotaxis of polymorphonuclear leukocytes (PMN's) in vitro have been studied. Response of rabbit PNM's in vitro to the chemotaxis was found to be suppressed by hydrocortisone succinate, chloroquine hydrochloride, cytochalasin B, colchicine and dibutyl cyclic AMP. On the other hand, 8-bromo-cyclic GMP enhanced the chemotaxis of PMN's.
摘要
已研究了多种药物对体外多形核白细胞（PMN）趋化性的影响。发现琥珀酸氢化可的松、盐酸氯喹、细胞松弛素B、秋水仙碱和二丁酰环磷酸腺苷可抑制兔PMN在体外对趋化性的反应。另一方面，8-溴环磷酸鸟苷增强了PMN的趋化性。
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