Meynard J L, el Amrani M, Meyohas M C, Fligny I, Gozlan J, Rozenbaum W, Roullet E, Frottier J
Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine, Paris, France.
Biomed Pharmacother. 1997;51(10):461-3. doi: 10.1016/s0753-3322(97)82326-8.
Neurological complications are particularly common during HIV infection. Among various opportunistic diseases, cytomegalovirus (CMV) is one of the most frequent causes of central and peripheral neurological manifestations. Previously, there have been several reports of cranial nerve infection by CMV, but to our knowledge, no cases of auditory nerve involvement have been described. We report two cases in which CMV infection was revealed by involvement of the VIIIth cranial nerves. Cytomegalovirus (CMV) infection is frequent in severely immunodeficient patients infected by human immunodeficiency virus (HIV). The main targets of CMV are the retina, gastrointestinal tract and central nervous system. We describe two cases in which neurologic CMV infection was revealed by hearing loss.
神经并发症在HIV感染期间尤为常见。在各种机会性疾病中,巨细胞病毒(CMV)是中枢和外周神经表现最常见的病因之一。此前,已有几例关于CMV感染脑神经的报道,但据我们所知,尚无听神经受累的病例描述。我们报告两例因第VIII脑神经受累而发现CMV感染的病例。巨细胞病毒(CMV)感染在感染人类免疫缺陷病毒(HIV)的严重免疫缺陷患者中很常见。CMV的主要靶器官是视网膜、胃肠道和中枢神经系统。我们描述两例因听力丧失而发现神经型CMV感染的病例。