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[慢性病会预防院内死亡吗?关于医院发病率信息中的矛盾与偏差]

[Do chronic diseases prevent intra-hospital mortality? Paradoxes and biases in information about hospital morbidity].

作者信息

Librero J, Peiró S

机构信息

Institut d'Investigació en Serveis de Salut.

出版信息

Gac Sanit. 1998 Sep-Oct;12(5):199-206. doi: 10.1016/s0213-9111(98)76473-8.

Abstract

OBJECTIVE

Previous studies have demonstrated how the incomplete codification of the secondary diagnostics can bias the estimation of the risk of in-hospital death based on clinical-administrative databases. The objective of this study is to measure the trend of the association between in-hospital mortality and the secondary diagnostics register in the Minimum Basic Data Set (MBDS) of the Valencian Community.

METHODS

The 14,161 admissions of persons over the age of 64 were extracted from the MBDS (years 1993-94) for: stroke (S), bacterial pneumonia (BN), myocardial infarction (MI) and congestive heart failure (CHF). The relation was measured between the availability of some additional diagnostics (selected to dispose of a group of heterogeneous chronic and acute processes), and the risk of in-hospital death, relative risk (RR) and adjusted odds ratios (aOR) were calculated per age, gender, length of stay and number of diagnoses.

RESULTS

Many of the conditions are associated with a reduced risk of death such as the diabetes mellitus (Mortality for stroke, RR: 0.58; aOR: 0.53), old myocardial infarction (mortality for myocardial infarction, RR: 0.40; aOR: 0.35) or hypertension (mortality for stroke, RR: 0.54; aOR: 0.49): this also occurs in angina, coronary atherosclerosis, aortic and mitral valve disease, atrial fibrillation, chronic obstructive pulmonary disease and urinary tract infection.

CONCLUSIONS

Although there maybe other explanations, such as the existence of a bias in the hospital selection, the explanation which is most in agreement with the findings is the presence of an information bias in the MBDS due to the tendency to register less information about chronic antecedents of the persons who die.

摘要

目的

先前的研究已经证明,二级诊断的编码不完整如何会基于临床管理数据库而使住院死亡风险的估计产生偏差。本研究的目的是衡量瓦伦西亚自治区最低基本数据集(MBDS)中住院死亡率与二级诊断登记之间的关联趋势。

方法

从MBDS(1993 - 1994年)中提取了14161例64岁以上患者的住院病例,这些病例涉及:中风(S)、细菌性肺炎(BN)、心肌梗死(MI)和充血性心力衰竭(CHF)。测量了一些额外诊断(选择用于处理一组异质性慢性和急性病症)的可得性与住院死亡风险之间的关系,按年龄、性别、住院时间和诊断数量计算相对风险(RR)和调整比值比(aOR)。

结果

许多病症与死亡风险降低相关,如糖尿病(中风死亡率,RR:0.58;aOR:0.53)、陈旧性心肌梗死(心肌梗死死亡率,RR:0.40;aOR:0.35)或高血压(中风死亡率,RR:0.54;aOR:0.49):心绞痛、冠状动脉粥样硬化、主动脉和二尖瓣疾病、心房颤动、慢性阻塞性肺疾病和尿路感染也存在这种情况。

结论

尽管可能有其他解释,如医院选择存在偏差,但与研究结果最相符的解释是,由于倾向于较少记录死亡患者的慢性病史,MBDS中存在信息偏差。

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