Ikehara T, Yamaguchi H, Miyamoto H
Department of Physiology, University of Tokushima School of Medicine, Japan.
J Med Invest. 1998 Aug;45(1-4):47-56.
We have studied the mechanisms of ion transport mediated by Na+/K(+)-pump and Na+,K+,Cl(-)-cotransport pathway of HeLa cells using Rb+ as an analog for K+, and proposed models of binding of ions for the transport pathways. Also, we clarified the relation between ion and water movements in the cells. Based on these findings, we have studied the effects of homogeneous and time-varying magnetic fields on the ion transport activity. The research presented here covers (i) brief explanations of our kinetic studies on the ion transport pathways for promoting understanding of the effects of magnetic fields on the pathways, (ii) our and other reports of the effects of magnetic fields on ion transport systems.
我们使用Rb⁺作为K⁺的类似物，研究了HeLa细胞中由Na⁺/K⁺泵和Na⁺、K⁺、Cl⁻共转运途径介导的离子转运机制，并提出了离子与转运途径结合的模型。此外，我们阐明了细胞中离子与水运动之间的关系。基于这些发现，我们研究了均匀磁场和时变磁场对离子转运活性的影响。这里展示的研究内容包括：（i）对我们关于离子转运途径的动力学研究的简要解释，以促进对磁场对这些途径影响的理解；（ii）我们以及其他关于磁场对离子转运系统影响的报告。
