Nadeau J H, Sankoff D
Genetics Department, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Trends Genet. 1998 Dec;14(12):495-501. doi: 10.1016/s0168-9525(98)01607-2.
Comparative maps record the history of chromosome rearrangements that have occurred during the evolution of plants and animals. Effective use of these maps in genetic and evolutionary studies relies on quantitative analyses of the patterns of segment conservation. We review the analytical methods that have been developed for characterizing these maps and evaluate their application to existing comparative maps mainly for plants and animals.
比较图谱记录了动植物进化过程中发生的染色体重排历史。在遗传和进化研究中有效利用这些图谱依赖于对片段保守模式的定量分析。我们回顾了为表征这些图谱而开发的分析方法，并评估了它们在主要针对动植物的现有比较图谱中的应用。
