Kenner T, Pessenhofer H, Schwaberger G
Pflugers Arch. 1976 Jun 22;363(3):263-5. doi: 10.1007/BF00594612.
A digital computer program was developed which allows to continuously represent the relation between heart rate and ventilation rate. Using this program, experiments in anesthetized rabbits were performed. We found periods of synchronization, periods of transient entrainment and escape, and periods of complete desynchronization. By testing the respective roles for the entrainment mechanism of ventilation rate and heart rate it was found that spontaneous adjustments of the ventilation rate play a more pronounced role. Thus, as soon as spontaneous or induced variations of the heart rate and/or the ventilation rate shift both rhythms close to synchronization, variations of the ventilation pattern, which seem to be of reflex nature, tend to induce entrainment.
开发了一种数字计算机程序,该程序可以持续呈现心率与通气率之间的关系。利用这个程序,在麻醉的兔子身上进行了实验。我们发现了同步期、短暂夹带和逸出期以及完全不同步期。通过测试通气率和心率夹带机制的各自作用,发现通气率的自发调整起了更显著的作用。因此,一旦心率和/或通气率的自发或诱发变化使两种节律接近同步,似乎具有反射性质的通气模式变化就倾向于诱发夹带。