[Individual computer-assisted pharmacotherapy in Parkinson disease].

The authors examined whether it is valid to use electromyographic signs for control of both the efficiency of pharmacotherapy and an individual choice of drugs. A new computer method of processing of muscular electrical potentials' registered-by supradermal electrodes is proposed. The method permitted quantitation of electromyographic signs of the main symptoms of Parkinson's disease (tremor, rigidity, akinesia). Based on the signs obtained, a system of automatic diagnosis of the main symptoms of Parkinson's disease by a separate muscle was designed. This method was used in examination of 72 patients with different clinical forms of Parkinson's disease in the course of selectivity pharmatherapy for them. The method can be used for more precise diagnosis of the disease of clinical forms, for an individual choice of drugs during long-term antiparkinsonic mono- and combined therapy and for evaluation of efficiency of the treatment performed.