Barreto Ramón P, Corral Mata M E, Muñoz López J, Boncompte Vilanova M P, Sebastián Gallego R, Solà Gonfaus M
ABS Les Planes, Sant Joan Despí, Barcelona.
Aten Primaria. 1998 Nov 15;22(8):491-6.
a) To determine the prevalence of psychological malaise (PM) in the population-group attending. b) To find the sensitivity and specificity of diagnoses of anxiety-depression made by doctors and on the Goldberg Anxiety and Depression Scale (GADS), using the Mini International Neuropsychiatric Interview (MINI) as gold standard. c) To study whether there are factors that might affect PM's detection.
Crossover study.
Urban health centre.
252 patients from the general population between 15 and 65 who attended for consultation for 10 days in May 1997.
The clinical diagnosis of 1266 patients was recorded. A sample was selected at random, to whom both the GADS and the MINI were administered, so as to compare the diagnoses. The prevalence of PM according to clinical judgement was similar to that found with the MINI (40.9%), with a clear overdiagnosis on the GADS. Clinical judgement mainly detected the anxiety component. The results of clinical judgement and the GADS were compared with the MINI (gold standard), and sensitivity of 73.78% and specificity of 72.48% were found for clinical judgement, and sensitivity of 95% and specificity of 64.4% for the GADS.
Prevalence of PM is high. The GADS showed it was useful for PM screening. The doctor's ability to detect PM is considerable. We found no variables that might affect diagnostic error.
a) 确定前来就诊人群中心理不适（PM）的患病率。b) 以迷你国际神经精神访谈（MINI）作为金标准，找出医生诊断及使用戈德堡焦虑抑郁量表（GADS）诊断焦虑抑郁的敏感性和特异性。c) 研究是否存在可能影响PM检测的因素。
交叉研究。
城市健康中心。
1997年5月连续10天前来就诊的252名15至65岁的普通人群患者。
记录了1266名患者的临床诊断。随机抽取一个样本，对其同时进行GADS和MINI测试，以便比较诊断结果。根据临床判断得出的PM患病率与MINI得出的结果相似（40.9%），而GADS存在明显的过度诊断情况。临床判断主要检测出了焦虑成分。将临床判断结果和GADS结果与MINI（金标准）进行比较，临床判断的敏感性为73.78%，特异性为72.48%；GADS的敏感性为95%，特异性为64.4%。
PM患病率较高。GADS表明其对PM筛查有用。医生检测PM的能力较强。我们未发现可能影响诊断错误的变量。
