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自发性高血压大鼠与正常血压大鼠尾动脉粘弹性特性的比较。

Comparison of the visco-elastic properties of the tail artery in spontaneously hypertensive and normotensive rats.

作者信息

Busse R, Bauer R D, Summa Y, Körner H, Pashch T

出版信息

Pflugers Arch. 1976 Jul 30;364(2):175-81. doi: 10.1007/BF00585187.

DOI:10.1007/BF00585187
PMID:986626
Abstract

The quasistatic and dynamic elastic behaviour of the tail artery of male normotensive (NCR) and spontaneously hypertensive (SHR) rats was determined in vitro. The tone of the smooth muscle was enhanced by norepinephrine and diminished by papaverine. The circumferential wall stress was changed by varying the transmural pressure level. The experimental procedure was the same as that used in a previous investigation (Bauer and Pasch, 1971). The circumferential (tangential) elastic wall modulus Et was calculated from the mean internal and external radii determined at each pressure level and from dynamic pressure-volume recordings in the frequency range between 0.03 and 20 HZ. The calculation was based on a formula valid for thick-walled, longitudinally constrained vessels.

摘要

在体外测定了雄性正常血压(NCR)大鼠和自发性高血压(SHR)大鼠尾动脉的准静态和动态弹性行为。去甲肾上腺素增强平滑肌张力,罂粟碱减弱平滑肌张力。通过改变跨壁压力水平来改变周向壁应力。实验程序与先前研究(Bauer和Pasch,1971)中使用的相同。周向(切向)弹性壁模量Et由在每个压力水平测定的平均内半径和外半径以及在0.03至20赫兹频率范围内的动态压力-容积记录计算得出。该计算基于一个对厚壁、纵向受限血管有效的公式。

相似文献

1
Comparison of the visco-elastic properties of the tail artery in spontaneously hypertensive and normotensive rats.自发性高血压大鼠与正常血压大鼠尾动脉粘弹性特性的比较。
Pflugers Arch. 1976 Jul 30;364(2):175-81. doi: 10.1007/BF00585187.
2
The quasistatic and dynamic circumferential elastic modulus of the rat tail artery studied at various wall stresses and tones of the vascular smooth muscle.
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3
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The distensibility of the resistance vessels in spontaneously hypertensive rats (SHR) as compared with normotensive control rats (NCR).与正常血压对照大鼠(NCR)相比,自发性高血压大鼠(SHR)中阻力血管的扩张性。
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引用本文的文献

1
Dependence of elastic and viscous properties of elastic arteries on circumferential wall stress at two different smooth muscle tones.
Pflugers Arch. 1981 May;390(2):113-9. doi: 10.1007/BF00590192.
2
The contribution of the parallel and series elastic components to the dynamic properties of the rat tail artery under two different smooth muscle tones.
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3
Intravital measurement of arteriolar pressure and tangential wall stress in normotensive and spontaneously hypertensive rats (established hypertension).
Experientia. 1978 Jul 15;34(7):865-7. doi: 10.1007/BF01939669.
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Contribution of smooth muscle to arterial wall mechanics.

本文引用的文献

1
The dynamic elastic properties of the arterial wall.动脉壁的动态弹性特性
J Physiol. 1961 May;156(3):458-69. doi: 10.1113/jphysiol.1961.sp006687.
2
Reactivity to noradrenaline of aortic strips and portal veins from spontaneously hypertensive and normotensive rats.自发性高血压大鼠和正常血压大鼠的主动脉条和门静脉对去甲肾上腺素的反应性。
Acta Physiol Scand. 1971 Feb;81(2):176-81. doi: 10.1111/j.1748-1716.1971.tb04890.x.
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Background of increased flow resistance and vascular reactivity in spontaneously hypertensive rats.自发性高血压大鼠血流阻力增加和血管反应性增强的背景。
Basic Res Cardiol. 1979 Jan-Feb;74(1):1-9. doi: 10.1007/BF01907680.
Acta Physiol Scand. 1970 Sep;80(1):93-106. doi: 10.1111/j.1748-1716.1970.tb04773.x.
4
The quasistatic and dynamic circumferential elastic modulus of the rat tail artery studied at various wall stresses and tones of the vascular smooth muscle.
Pflugers Arch. 1971;330(4):335-46. doi: 10.1007/BF00588585.
5
The distensibility of the resistance vessels in spontaneously hypertensive rats (SHR) as compared with normotensive control rats (NCR).与正常血压对照大鼠(NCR)相比,自发性高血压大鼠(SHR)中阻力血管的扩张性。
Acta Physiol Scand. 1974 Jan;90(1):57-68. doi: 10.1111/j.1748-1716.1974.tb05562.x.
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Reactivity of vascular smooth muscle from normal and hypertensive rats: effect of several cations.正常大鼠和高血压大鼠血管平滑肌的反应性:几种阳离子的作用
Fed Proc. 1974 Feb;33(2):127-32.
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Cyclic amp blood vessels of spontnaeously hypertensive rat.自发性高血压大鼠的环磷酸腺苷血管
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8
Effects of papaverine on smooth muscle and their mechanisms.罂粟碱对平滑肌的作用及其机制。
Pharmacol Res Commun. 1974 Apr;6(2):97-115. doi: 10.1016/s0031-6989(74)80018-4.
9
Adenyl cyclase-phosphodiesterase system in arterial smooth muscle.动脉平滑肌中的腺苷酸环化酶-磷酸二酯酶系统
Life Sci I. 1972 Sep 1;11(17):817-24.
10
Cyclic adenosine monophosphate and hypertension in rats.环磷酸腺苷与大鼠高血压
Science. 1973 Feb 23;179(4075):807-9. doi: 10.1126/science.179.4075.807.