McCulloch G L, Sinnatamby R, Stewart S, Goddard M, Flower C D
Department of Radiology, Papworth Hospital, Papworth Everard, Cambridge, UK.
Eur Radiol. 1998;8(9):1669-73. doi: 10.1007/s003300050609.
MALToma of the lung is rare and advances in molecular techniques have only recently allowed accurate diagnostic classification of the previously termed "pseudolymphomas" by demonstrating that many are monoclonal B-cell proliferations of MALT tissue and therefore true low-grade lymphomas. No significant previous contribution was found in the literature regarding the high-resolution CT appearance (HRCT) of these tumours. We describe the high-resolution CT appearances in five cases presenting to our institution from 1994 to 1997. The HRCT scans (1-mm sections at 10- to 15-mm intervals) were performed as the opacities seen radiographically were thought to be part of a diffuse lung process. In one patient a spiral sequence was performed through the main airway. Multifocal, ill-defined nodules containing air bronchograms were seen in four cases and focal lobar consolidation in one case. Interlobular septal thickening, centrilobular micronodules and bronchial wall thickening were seen in two cases. Mediastinal lymphadenopathy and pleural reaction do not appear to be characteristic features. The appearance of multifocal consolidation is similar to that seen in bronchoalveolar cell carcinoma and cryptogenic organising pneumonia.
肺黏膜相关淋巴组织淋巴瘤(MALToma)较为罕见,分子技术的进步直到最近才使得对先前称为“假性淋巴瘤”的疾病进行准确的诊断分类,这是通过证明许多此类疾病是MALT组织的单克隆B细胞增殖,因此属于真正的低度淋巴瘤。此前文献中未发现有关这些肿瘤的高分辨率CT表现(HRCT)的重要贡献。我们描述了1994年至1997年在我院就诊的5例患者的高分辨率CT表现。由于影像学上所见的肺部模糊影被认为是弥漫性肺部病变的一部分,因此进行了HRCT扫描(层厚1mm,层间距10至15mm)。1例患者通过主气道进行了螺旋扫描。4例可见多发、边界不清的结节,内见空气支气管征,1例可见局灶性肺叶实变。2例可见小叶间隔增厚、小叶中心微结节和支气管壁增厚。纵隔淋巴结肿大和胸膜反应似乎并非其特征性表现。多灶性实变的表现与细支气管肺泡癌和隐源性机化性肺炎所见相似。