Moser E
Department of Nuclear Medicine, Albert-Ludwigs-University of Frieburg, Germany.
Exp Clin Endocrinol Diabetes. 1998;106 Suppl 4:S63-5. doi: 10.1055/s-0029-1212060.
The presented overview summarizes the results of radioiodine treatment in patients with different forms of Plummer's disease. From the beginning the outcome defined as elimination of autonomy was excellent in the unifocal autonomous adenomas, but unsatisfactory in multifocal and disseminated autonomy using a fixed dose concept. The "dosimetric compromise" (= reducing the dose and defining the total gland as the target volume) yielded in these two variants of autonomy satisfactory results comparable to those of the unifocal form, since the dose was chosen according to the amount of functional autonomy measured by the Tc-99m-uptake in the thyroid gland under TSH-suppression.
本综述总结了不同形式的普卢默病患者放射性碘治疗的结果。从一开始，在单灶自主性腺瘤中，定义为自主性消除的结果非常好，但在多灶性和弥漫性自主性情况下，使用固定剂量概念的结果并不理想。“剂量测定折衷法”（即降低剂量并将整个腺体定义为靶体积）在这两种自主性变体中产生了与单灶形式相当的满意结果，因为剂量是根据在促甲状腺激素抑制状态下通过甲状腺中锝-99m摄取量测量的功能性自主性量来选择的。
