Radioiodine treatment of Plummer's disease.

The presented overview summarizes the results of radioiodine treatment in patients with different forms of Plummer's disease. From the beginning the outcome defined as elimination of autonomy was excellent in the unifocal autonomous adenomas, but unsatisfactory in multifocal and disseminated autonomy using a fixed dose concept. The "dosimetric compromise" (= reducing the dose and defining the total gland as the target volume) yielded in these two variants of autonomy satisfactory results comparable to those of the unifocal form, since the dose was chosen according to the amount of functional autonomy measured by the Tc-99m-uptake in the thyroid gland under TSH-suppression.