一家医院普通内科门诊的药物使用情况，特别提及抗高血压药和抗糖尿病药。
Drug utilization in a hospital general medical outpatient clinic with particular reference to antihypertensive and antidiabetic drugs.
作者信息
Yuen Y H, Chang S, Chong C K, Lee S C, Critchley J A, Chan J C
机构信息
Department of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories.
出版信息
J Clin Pharm Ther. 1998 Aug;23(4):287-94. doi: 10.1046/j.1365-2710.1998.00161.x.
OBJECTIVES
To examine the prescribing patterns, particularly antihypertensive and antidiabetic drugs, in a hospital outpatient clinic and to evaluate the expenditure incurred.
METHODS
Prescriptions from a general medical outpatient clinic in a teaching hospital were collected for 4 weeks. Drug expenditures were calculated.
RESULTS
A total of 622 prescriptions containing 1903 items were collected. Antihypertensive and antidiabetic drugs accounted for 25.9 and 9.1% usage, respectively. Calcium channel blocking agents, angiotensin converting enzyme inhibitors and beta-blocking agents were the most popular antihypertensive drugs used. Sulphonylureas were the most frequently prescribed antidiabetic agents. Amlodipine, doxazosin and sotalol accounted for 4.5% of all prescription items but 27.8% of the total drug expenditure.
CONCLUSION
The use of antihypertensive and antidiabetic drugs accounted for most of the drug usage in this study. Use of newer and more expensive agents has further increased drug expenditure. Monitoring drug usage and their correlations with clinical outcomes are warranted.
目的
研究一家医院门诊的处方模式，尤其是抗高血压药和抗糖尿病药的处方模式，并评估所产生的费用。
方法
收集一家教学医院普通内科门诊4周的处方，计算药物费用。
结果
共收集到622张处方，包含1903项药品。抗高血压药和抗糖尿病药的使用分别占25.9%和9.1%。钙通道阻滞剂、血管紧张素转换酶抑制剂和β受体阻滞剂是最常用的抗高血压药。磺脲类药物是最常处方的抗糖尿病药物。氨氯地平、多沙唑嗪和索他洛尔占所有处方药品的4.5%，但占总药物费用的27.8%。
结论
在本研究中，抗高血压药和抗糖尿病药的使用占药物使用的大部分。使用更新、更昂贵的药物进一步增加了药物费用。有必要监测药物使用情况及其与临床结果的相关性。
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