Zhou G, Huang G, Ren L
Department of Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 1997 Mar;11(2):76-9.
In order to investigate the histological and stereological change of the rapidly expanded skin tube, 15 Japanese Long Ear Rabbits were divided into 3 groups: (1) Rapid expansion group, injecting once a day for 7 days; (2) Routine expansion group, injecting every 3 days for 21 days and (3) Control group, no expander implanted. The results showed that: in the rapid expansion group, the thickness of the epidermis and dermis were both increased, fibroblast proliferation was active, a large amount of new capillaries was observed, the collagen fiber was in loose type, and the mitochondria and rough endoplasmic net of epithelial cell were increased. In the routine expansion group, similar changes were observed. The vascular density and volume fraction were significantly higher in rapid expansion group than those in the control group (P < 0.05). It was concluded that the rapid expansion of skin tube was feasible.
为了研究快速扩张皮管的组织学和体视学变化，将15只日本大耳白兔分为3组：（1）快速扩张组，每天注射1次，共7天；（2）常规扩张组，每3天注射1次，共21天；（3）对照组，未植入扩张器。结果显示：快速扩张组中，表皮和真皮厚度均增加，成纤维细胞增殖活跃，可见大量新生毛细血管，胶原纤维呈疏松型，上皮细胞的线粒体和粗面内质网增多。常规扩张组也观察到类似变化。快速扩张组的血管密度和体积分数显著高于对照组（P<0.05）。结论是皮管快速扩张是可行的。
