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1型人类免疫缺陷病毒(HIV)感染儿童的视网膜微血管病变

Retinal microvasculopathy in human immunodeficiency type 1 (HIV)-infected children.

作者信息

Tejada P, Sarmiento B, Ramos J R

机构信息

Department of Ophthalmology, Hospital Doce de Octubre, Madrid, Spain.

出版信息

Int Ophthalmol. 1997;21(6):319-21. doi: 10.1023/a:1006027318983.

DOI:10.1023/a:1006027318983
PMID:9869339
Abstract

PURPOSE

To report two cases of retinal peripheral lesions in vertically HIV-infected children.

METHODS

Complete ophthalmological examinations were performed in both cases over a period of four years.

RESULTS

We found retinal peripheral lesions in four eyes of two patients who were referred to us for routine examination. Both cases showed focal, segmental and white patches around the vessel wall in the far periphery and at the equator. These findings hardly changed after 3.5 and 2.5 years of follow-up, respectively. We suppose the cause of these lesions is an immune-mediated reaction.

CONCLUSIONS

Even although there is a low incidence of retinal alterations in pediatric patients infected by HIV, we believe that complete and systematic ophthalmic examinations should be performed in these children.

摘要

目的

报告两例垂直感染人类免疫缺陷病毒(HIV)儿童的视网膜周边病变病例。

方法

在四年时间里对两例患者均进行了全面的眼科检查。

结果

我们在因常规检查前来就诊的两名患者的四只眼中发现了视网膜周边病变。两例均显示在远周边部和赤道部血管壁周围有局灶性、节段性白色斑块。分别经过3.5年和2.5年的随访后,这些表现几乎没有变化。我们推测这些病变的原因是免疫介导反应。

结论

尽管HIV感染儿科患者中视网膜改变的发生率较低,但我们认为应对这些儿童进行全面系统的眼科检查。

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本文引用的文献

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Risk factors for cotton-wool spots and for cytomegalovirus retinitis in patients with human immunodeficiency virus infection.人类免疫缺陷病毒感染患者出现棉絮斑和巨细胞病毒性视网膜炎的危险因素。
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Perivasculitis of the retinal vessels as an important sign in children with AIDS-related complex.
视网膜血管周围炎是艾滋病相关综合征患儿的一项重要体征。
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Infection of the retina by human immunodeficiency virus type I.人类免疫缺陷病毒I型对视网膜的感染。
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Prevalence and significance of acquired immunodeficiency syndrome-related retinal microvasculopathy.获得性免疫缺陷综合征相关视网膜微血管病变的患病率及意义
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Retinal toxicity in human immunodeficiency virus-infected children treated with 2',3'-dideoxyinosine.
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