Lee S H, Chen S A, Tai C T, Chiang C E, Wen Z C, Chen Y J, Yu W C, Fong A N, Huang J L, Cheng J J, Chang M S
Department of Medicine and Institute of Clinical Medicine, National Yang-Ming University, Veterans General Hospital-Taipei and Kaohsiung, Taiwan, R.O.C.
J Interv Card Electrophysiol. 1997 Dec;1(4):305-10. doi: 10.1023/a:1009785127119.
Among a consecutive series of 600 patients who underwent radiofrequency catheter ablation for AV node reentrant tachycardia, 14 patients (age 29-76 years) had a prolonged AH interval during sinus rhythm (172 +/- 18 ms, range 140 to 200). Seven of them had unsuccessful ablation during the previous ablation sessions. Eight patients with anterograde dual AV node pathway physiology received anterograde slow pathway ablation, and the other 6 patients without dual-pathway physiology received retrograde fast pathway ablation. All patients had successful elimination of AV nodal reentrant tachycardia after a mean of 4 +/- 4 radiofrequency applications, power level 36 +/- 6 watts and a pulse duration of 42 +/- 4 seconds. The postablation AH interval remained unchanged. During a follow-up period of 25 +/- 13 months, one patient who received slow pathway ablation developed 2:1 AV block with syncope. As compared with the other 586 patients without a prolonged AH interval, these 14 patients had significantly poorer anterograde AV nodal function and lower incidence of anterograde dual AV node physiology (P < 0.01). We concluded that slow pathway ablation in patients with dual pathway physiology, and retrograde fast pathway ablation in patients without dual pathway physiology were effective and safe in patients with a prolonged AH interval. However, delayed onset of symptomatic AV block is possible and careful follow-up is necessary.
在连续600例行房室结折返性心动过速射频导管消融术的患者中,14例患者(年龄29 - 76岁)在窦性心律时AH间期延长(172±18毫秒,范围140至200毫秒)。其中7例患者在之前的消融术中消融失败。8例具有前传双房室结径路生理特征的患者接受了前传慢径路消融,另外6例无双径路生理特征的患者接受了逆传快径路消融。所有患者在平均4±4次射频应用、功率36±6瓦、脉冲持续时间42±4秒后均成功消除了房室结折返性心动过速。消融后AH间期保持不变。在25±13个月的随访期内,1例接受慢径路消融的患者发生了伴有晕厥的2:1房室传导阻滞。与其他586例AH间期未延长的患者相比,这14例患者的前传房室结功能明显较差,前传双房室结生理特征的发生率较低(P<0.01)。我们得出结论,对于有双径路生理特征的患者进行慢径路消融,以及对于无双径路生理特征的患者进行逆传快径路消融,在AH间期延长的患者中是有效且安全的。然而,症状性房室传导阻滞可能会延迟出现,因此需要仔细随访。