细胞黏菌中聚集的分化：盘基网柄菌中自主信号细胞的出现。

Differentiation for aggregation in the cellular slime moulds: the emergence of autonomously signalling cells in Dictyostelium discoideum.

作者信息

Raman R K, Hashimoto Y, Cohen M H, Robertson A

出版信息

J Cell Sci. 1976 Jul;21(2):243-59. doi: 10.1242/jcs.21.2.243.

DOI:10.1242/jcs.21.2.243

Abstract

The results of experiments on small populations of Dictyostelium discoideum, directed towards the measurement of the development in time of the competence of the cells to signal autonomously, are reported. This competence is quantified by X3, the intrinsic probability that a given cell may turn autonomous. The data show an early exponential growth in time of X3, followed by saturation. The saturation value depends on the population size suggesting that the differentiation is a co-operative phenomenon. The differentiation of autonomous cells starts roughly 7 h after the removal of food and saturates within 21 h.

摘要

本文报告了针对盘基网柄菌小群体进行的实验结果，这些实验旨在测量细胞自主发出信号能力随时间的发展情况。这种能力通过X3进行量化，即给定细胞转变为自主状态的内在概率。数据显示，X3随时间呈早期指数增长，随后趋于饱和。饱和值取决于群体大小，这表明分化是一种合作现象。自主细胞的分化大约在去除食物后7小时开始，并在21小时内达到饱和。