感官视紫红质I和噬盐视紫红质中视黄醛发色团6s-反式构象的测定。
Determination of 6s-trans conformation of retinal chromophore in sensory rhodopsin I and phoborhodopsin.
作者信息
Wada A, Akai A, Goshima T, Takahashi T, Ito M
机构信息
Kobe Pharmaceutical University, Japan.
出版信息
Bioorg Med Chem Lett. 1998 Jun 2;8(11):1365-8. doi: 10.1016/s0960-894x(98)00233-9.
PMID:9871767
Abstract
8,16-Ethanoretinal 3 was synthesized from 2-methylcyclohexanone. From the binding experiments of 3 and 8,18-ethanoretinal 2 with apoproteins of sensory rhodopsin I and phoborhodopsin, it was found that retinal was incorporated as 6s-trans conformation in the both proteins.
摘要
8,16-乙基视黄醛3由2-甲基环己酮合成。通过3和8,18-乙基视黄醛2与视紫红质I和嗜盐视紫红质脱辅基蛋白的结合实验发现，视黄醛在这两种蛋白质中均以6s-反式构象掺入。
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