Tomono H, Fujioka S, Kato K, Yoshida K, Nimura Y
Department of Surgery, Kiryu Kousei General Hospital, Gunma, Japan.
Surg Today. 1998;28(12):1304-6. doi: 10.1007/BF02482821.
A 72-year-old woman with a history of early breast cancer suffered a fracture of the eighth thoracic vertebra resulting in paraplegia. Magnetic resonance imaging (MRI) showed spinal cord compression by a tumor between the ninth and tenth thoracic vertebrae. Local radiotherapy was begun under the diagnosis of metastatic breast cancer, but bone marrow aspiration and biopsy subsequently revealed plasma-cell proliferation rather than adenocarcinoma. This case report serves to demonstrate that clinicians should consider multiple myeloma as a cause of lytic bone lesions without extraskeletal metastases even in patients with a history of breast cancer.
一名有早期乳腺癌病史的72岁女性发生了第八胸椎骨折，导致截瘫。磁共振成像（MRI）显示第九和第十胸椎之间有一个肿瘤压迫脊髓。在诊断为转移性乳腺癌后开始了局部放疗，但骨髓穿刺和活检随后显示为浆细胞增殖而非腺癌。本病例报告旨在表明，即使是有乳腺癌病史的患者，临床医生也应将多发性骨髓瘤视为无骨外转移的溶骨性骨病变的一个病因。
