经皮乙醇注射治疗肝细胞癌后发生肝梗死。

Hepatic infarction following percutaneous ethanol injection therapy for hepatocellular carcinoma.

作者信息

Seki T, Wakabayashi M, Nakagawa T, Imamura M, Tamai T, Nishimura A, Yamashiki N, Okamura A, Inoue K

机构信息

Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan.

出版信息

Eur J Gastroenterol Hepatol. 1998 Nov;10(11):915-8. doi: 10.1097/00042737-199811000-00003.

DOI:10.1097/00042737-199811000-00003

PMID:9872612

Abstract

We report on two patients who developed hepatic infarction after undergoing percutaneous ethanol injection therapy (PEIT) for hepatocellular carcinoma (HCC). In both cases, liver function parameters deteriorated immediately after the ethanol injection, and enhanced computed tomography images showed a wedge-shaped avascular low-density area due to hepatic infarction. In one patient, PEIT was performed for a nodule treated with transcatheter arterial infusion (TAI) using a suspension of styrene maleic acid neocarzinostatin (SMANCS) 4 weeks before. In the other patient, TAI with SMANCS had been carried out 14 months previously for a different nodule in the same segment where the nodule treated with PEIT was located. When PEIT is used for patients with HCC who have previously undergone TAI, especially with SMANCS, PEIT may induce hepatic infarction.

摘要

我们报告了两名肝细胞癌（HCC）患者，他们在接受经皮乙醇注射治疗（PEIT）后发生了肝梗死。在这两例病例中，乙醇注射后肝功能参数立即恶化，增强计算机断层扫描图像显示由于肝梗死导致的楔形无血管低密度区。在一名患者中，4周前曾对一个结节进行经动脉化疗栓塞（TAI），使用的是苯乙烯马来酸新制癌菌素（SMANCS）混悬液，之后对该结节进行了PEIT。在另一名患者中，14个月前曾对同一肝段中与接受PEIT治疗的结节不同的另一个结节进行了SMANCS TAI。当对先前接受过TAI（尤其是使用SMANCS）的HCC患者使用PEIT时，PEIT可能会诱发肝梗死。