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心脏乳头状纤维弹性瘤:年轻人缺血性卒中的罕见病因。

Cardiac papillary fibroelastoma: aA rare cause of ischemic stroke in the young.

作者信息

Giannesini C, Kubis N, N'Guyen A, Wassef M, Mikol J, Woimant F

机构信息

Department of Neurology, Hôpital Lariboisière, Paris, France.

出版信息

Cerebrovasc Dis. 1999 Jan-Feb;9(1):45-9. doi: 10.1159/000015895.

Abstract

Among etiologies of stroke in young adults, primary cardiac tumors are very rare. We report the case of a 37-year-old woman who was admitted for an ischemic stroke in the right middle cerebral artery region. Etiologic investigations revealed, after transthoracic and transesophageal echocardiography, an aortic valve tumor. Treatment was first medical with anticoagulation, then surgical. Histological examination showed a papillary fibroelastoma. After a review of the literature, the possible mechanisms of the ischemic event are discussed and lead to the conclusion that this tumor must be surgically excised, even if asymptomatic, because of recurrent ischemic complications responsible for myocardial infarction, stroke and sudden death.

摘要

在年轻成年人中风的病因中,原发性心脏肿瘤非常罕见。我们报告一例37岁女性,因右侧大脑中动脉区域缺血性中风入院。病因学检查在经胸和经食管超声心动图检查后发现一个主动脉瓣肿瘤。治疗首先采用抗凝药物治疗,然后进行手术。组织学检查显示为乳头状纤维弹性瘤。在回顾文献后,讨论了缺血事件的可能机制,并得出结论,即使无症状,该肿瘤也必须手术切除,因为其反复出现的缺血性并发症可导致心肌梗死、中风和猝死。

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