Say J
Department of Adult Nursing (South), University of Hertfordshire, Hatfield.
Nurs Crit Care. 1997 Mar-Apr;2(2):83-7.
Developments in critical care medicine have increased the chances of survival of those patients with severe trauma or established sepsis. However, such patients often have a prolonged critical illness, and the ensuing catabolic response can have detrimental effects causing a depletion of body weight, tissue mass and stored nutrients. In order to facilitate treatment and minimise the effects of these catabolic changes, both the mediators of this response and the response itself have been studied. This paper explores the current understanding of the metabolic changes that occur in trauma and sepsis, and how these changes alter carbohydrate, fat and protein metabolism.
重症监护医学的发展增加了严重创伤或已确诊脓毒症患者的存活几率。然而，这类患者往往患有长期危重病，随之产生的分解代谢反应可能产生有害影响，导致体重减轻、组织量减少和储存营养物质耗尽。为了便于治疗并尽量减少这些分解代谢变化的影响，人们对这种反应的介质及其反应本身都进行了研究。本文探讨了目前对创伤和脓毒症中发生的代谢变化的理解，以及这些变化如何改变碳水化合物、脂肪和蛋白质代谢。
