Barawkar D A, Linkletter B, Bruice T C
Department of Chemistry, University of California, Santa Barbara 93106, USA.
Bioorg Med Chem Lett. 1998 Jun 16;8(12):1517-20. doi: 10.1016/s0960-894x(98)00251-0.
The synthesis of novel fully protected guanidinium linked dinucleoside for incorporation into oligonucleotide using solid-phase DNA synthesis methodology was developed. The three different protecting groups selected allow different deprotection conditions.
开发了一种新型的完全保护的胍基连接二核苷的合成方法，用于通过固相DNA合成方法将其掺入寡核苷酸中。所选择的三种不同保护基团允许不同的脱保护条件。
