Nasir A I, Gundersen L L, Rise F, Antonsen O, Kristensen T, Langhelle B, Bast A, Custers I, Haenen G R, Wikström H
Department of Chemistry, University of Oslo, Norway.
Bioorg Med Chem Lett. 1998 Jul 21;8(14):1829-32. doi: 10.1016/s0960-894x(98)00313-8.
Esters, ethers, carbonates and carbamates of 1-indolizinols and azaindolizinols exhibit a profound inhibition of lipid peroxidation in vitro. The antioxidants were prepared by cyclization of pyridines and diazines with diphenylcyclopropenone followed by introduction of the O-substituent.
1-中氮茚醇和氮杂中氮茚醇的酯、醚、碳酸酯和氨基甲酸酯在体外对脂质过氧化表现出显著抑制作用。这些抗氧化剂是通过吡啶和二嗪与二苯基环丙烯酮环化，然后引入O-取代基制备而成的。
