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In vitro selection of phosphorothiolated aptamers.

作者信息

Jhaveri S, Olwin B, Ellington A D

机构信息

Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA.

出版信息

Bioorg Med Chem Lett. 1998 Sep 8;8(17):2285-90. doi: 10.1016/s0960-894x(98)00414-4.

Abstract

A pool of RNA molecules that contained exclusively phosphorothioate internucleoside linkages was used as a starting point for the selection of aptamers that bind to basic fibroblast growth factor (bFGF), and appear to act as heparin mimics.

摘要

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