疑似冠状动脉疾病患者冠状动脉和肱动脉中内皮依赖性血流介导的血管舒张功能
Endothelium-dependent flow-mediated vasodilation in coronary and brachial arteries in suspected coronary artery disease.
作者信息
Takase B, Uehata A, Akima T, Nagai T, Nishioka T, Hamabe A, Satomura K, Ohsuzu F, Kurita A
机构信息
Self Defense Force Central Hospital, Internal Medicine, Tokyo, Japan.
出版信息
Am J Cardiol. 1998 Dec 15;82(12):1535-9, A7-8. doi: 10.1016/s0002-9149(98)00702-4.
Previous studies showed a weak correlation between endothelial function of the coronary arteries as assessed by acetylcholine and brachial artery vasomotion during reactive hyperemia. When the same stimulus was used, we obtained a strong correlation between flow-mediated dilation in the coronary and brachial arteries (r=0.78, p <0.001), so that noninvasive assessment of flow-mediated dilation in the brachial artery could be used as a surrogate measure for coronary artery endothelial function.
先前的研究表明，通过乙酰胆碱评估的冠状动脉内皮功能与反应性充血期间肱动脉血管运动之间存在弱相关性。当使用相同的刺激时，我们发现冠状动脉和肱动脉的血流介导的扩张之间存在强相关性（r = 0.78，p <0.001），因此肱动脉血流介导的扩张的非侵入性评估可作为冠状动脉内皮功能的替代指标。
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