Levy E I, Scarrow A M, Kanal E, Rubin G, Yonas H, Kirby L
Department of Neurological Surgery, Presbyterian University Hospital, The University of Pittsburgh Medical Center, PA 15213, USA.
AJNR Am J Neuroradiol. 1998 Nov-Dec;19(10):1943-6.
Intraarterial thrombolytic therapy decreases mortality in the treatment of acute basilar artery occlusion. An acute decrease in cerebral blood flow (CBF) (<12 mL/100 g per minute) has been reported to invariably result in infarction. We report a case of acute basilar artery occlusion, recanalized within 90 minutes, with reversal of CBF of less than 6 mL/100 g per minute. After reperfusion, areas with persistent CBF of 6 mL/100 g per minute resulted in infarctions on subsequent CT studies. Parenchymal viability is possible after 90 minutes of posterior CBF of 6 mL/100 g per minute.
动脉内溶栓治疗可降低急性基底动脉闭塞的死亡率。据报道,脑血流量(CBF)急性减少(<12毫升/100克每分钟)必然会导致梗死。我们报告一例急性基底动脉闭塞病例,在90分钟内实现再通,CBF逆转至低于6毫升/100克每分钟。再灌注后,CBF持续为6毫升/100克每分钟的区域在后续CT研究中出现梗死。在CBF为6毫升/100克每分钟的情况下,90分钟后仍有可能实现实质存活。