Chung H S, Choi H K, Kim E M, Park M J, Chung K H, Yoo Y C
National Institute of Scientific Investigation, Seoul, Korea.
Arch Pharm Res. 1998 Jun;21(3):286-90. doi: 10.1007/BF02975289.
The abuse of zipeprol, an antitussive agent, was found to be most prevalent among young people in Korea. Because abusers take large doses of this drug for its hallucinogenic effects, fatalities from zipeprol overdose abuse have been on the rise since 1991. Since 1991, a total of 69 zipeprol-related deaths have occurred throughout the nation. A demographic study shows that in ninety six percent of cases involving ziperol alone, the victims were in their teens and twenties. The male/female ratio in zipeprol related death was 3.5:1. Most of these zipeprol-associated deaths occurred in the larger cities of Seoul and Inchon. The blood concentration of zipeprol ranged from 0.8 to 38.3 micrograms/mL in single drug involved deaths, while zipeprol varied from 0.1 to 35.3 micrograms/mL in zipeprol and dextromethorphan victims.
在韩国,镇咳药齐帕特罗的滥用在年轻人中最为普遍。由于滥用者为了其致幻作用而大量服用这种药物,自1991年以来,齐帕特罗过量滥用导致的死亡人数一直在上升。自1991年以来,全国共发生了69起与齐帕特罗相关的死亡事件。一项人口统计学研究表明,在仅涉及齐帕特罗的96%的案例中,受害者年龄在十几岁和二十几岁。齐帕特罗相关死亡事件中的男女比例为3.5:1。这些与齐帕特罗相关的死亡事件大多发生在首尔和仁川等大城市。在单一药物致死案例中,齐帕特罗的血药浓度范围为0.8至38.3微克/毫升,而在齐帕特罗和右美沙芬中毒受害者中,齐帕特罗的血药浓度范围为0.1至35.3微克/毫升。