因过量服用齐哌西定导致的罕见死亡。

An unusual death by zipeprol overdose.

作者信息

Kintz P, Tracqui A, Potard D, Petit G, Mangin P

机构信息

Institut de Médecine Légale, Strasbourg, France.

出版信息

Forensic Sci Int. 1994 Feb;64(2-3):159-63. doi: 10.1016/0379-0738(94)90226-7.

DOI:10.1016/0379-0738(94)90226-7

PMID:8175086

Abstract

Capillary gas chromatography coupled to mass spectrometry was employed to quantify zipeprol in biological fluids and tissues in a death attributed to oral zipeprol ingestion. The blood concentration of zipeprol was 6.69 mg/l. Hair analysis clearly indicated chronic drug abuse, with a concentration of 33.1 ng/mg. Results are discussed in the light of the existing literature.

摘要

采用毛细管气相色谱-质谱联用技术对一例因口服齐哌丙醇致死病例的生物体液和组织中的齐哌丙醇进行定量分析。齐哌丙醇的血液浓度为6.69毫克/升。毛发分析明确显示存在长期药物滥用情况，浓度为33.1纳克/毫克。结合现有文献对结果进行了讨论。