意大利撒丁岛中部多发性硬化症的流行病学研究。

An epidemiological study of multiple sclerosis in central Sardinia, Italy.

作者信息

Casetta I, Granieri E, Marchi D, Murgia S B, Tola M R, Ticca A, Lauria G, Govoni V, Murgia B, Pugliatti M

机构信息

Clinica Neurologica, Dipartimento di Discipline Medico-Chirurgiche della Comunicazione e del Comportamento, Centro Sclerosi Multipla, Università di Ferrara, Italy.

出版信息

Acta Neurol Scand. 1998 Dec;98(6):391-4. doi: 10.1111/j.1600-0404.1998.tb07319.x.

DOI:10.1111/j.1600-0404.1998.tb07319.x

PMID:9875616

Abstract

OBJECTIVES

To verify morbidity estimates in central Sardinia, Italy.

METHODS

A prevalence study was performed in the province of Nuoro, Central Sardinia, which has a population of 273,768 inhabitants (135,383 men and 138,385 women). A complete enumeration approach was adopted by using all possible case-collection sources.

RESULTS

On prevalence day, December 31, 1993, 394 subjects (124 men and 270 women) living in the study area were known to suffer from definite and probable MS, giving a crude prevalence rate of 143.9 cases per 100,000 people, 91.6 for males and 195.11 for females. The crude prevalence estimated on December 31, 1985, based on 282 MS cases alive in the study area, was 102.94 per 100,000.

CONCLUSION

This study reinforced central Sardinia's position as a high and rising prevalence area for MS.

摘要

目的

验证意大利撒丁岛中部的发病率估计值。

方法

在撒丁岛中部的努奥罗省进行了一项患病率研究，该省有273,768名居民（男性135,383人，女性138,385人）。采用了一种完整的枚举方法，利用所有可能的病例收集来源。

结果

在患病率调查日，即1993年12月31日，已知居住在研究区域的394名受试者（124名男性和270名女性）患有确诊和疑似多发性硬化症，粗患病率为每10万人中有143.9例，男性为91.6例，女性为195.11例。根据1985年12月31日研究区域内282例存活的多发性硬化症病例估计的粗患病率为每10万人中有102.94例。