Barrett J
Parasitology. 1976 Aug;73(1):109-21. doi: 10.1017/s0031182000051374.
The initial process in the hatching mechanism of Ascaris eggs is the sudden onset of permeability in the previously impermeable ascaroside membrane. During this change the ascaroside membrane remains intact and no chemical changes can be detected. Using the molecular probe 1-anilino-8-naphthalene sulphonic acid no conformational changes were detected in the ascaroside membrane during the induction of permeability. It is suggested that either the permeability change is due to a very localized chemical or conformational change, not detectable by conventional analytical techniques, or the change is due to mechanical damage of the ascaroside membrane, brought about by the activity of the infective larva.
蛔虫卵孵化机制的初始过程是，先前不透水的ascaroside膜突然开始具有通透性。在此变化过程中，ascaroside膜保持完整，未检测到化学变化。使用分子探针1-苯胺基-8-萘磺酸，在诱导通透性期间未检测到ascaroside膜的构象变化。有人提出，通透性变化要么是由于非常局部的化学或构象变化（传统分析技术无法检测到），要么是由于感染性幼虫的活动对ascaroside膜造成的机械损伤。
