Glasauer S, Dieterich M, Brandt T
Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University, München, Germany.
Neuroreport. 1998 Dec 1;9(17):3841-5. doi: 10.1097/00001756-199812010-00014.
Static vestibulo-ocular brain stem syndromes characterized by skew deviation, a vertical disconjugacy of the eyes, and ocular torsion are the result of a vestibular tone imbalance in the frontal (roll) plane. Similar physiological changes in static eye position, ocular counter-roll and conjugated deviations of vertical eye position, are caused by the influence of gravity mediated by the utricles. These observations prompted our approach with the model described here: based on the known deviations of static eye position, we devised a three-dimensional mathematical model of otolith-ocular function including detailed brain stem anatomy. This model is able to explain and predict the differential effects of unilateral and bilateral peripheral or central vestibular lesions on static eye position in roll, pitch, and yaw planes.
以眼斜、双眼垂直非共轭及眼球扭转为特征的静态前庭眼脑干综合征是额状面（横滚）前庭张力失衡的结果。静态眼位、眼球反向转动以及垂直眼位共轭偏差的类似生理变化是由椭圆囊介导的重力影响所致。这些观察结果促使我们采用此处描述的模型：基于已知的静态眼位偏差，我们设计了一个耳石眼功能的三维数学模型，其中包括详细的脑干解剖结构。该模型能够解释和预测单侧及双侧外周或中枢前庭病变对横滚、俯仰和偏航平面静态眼位的不同影响。
