Yanagihara M, Fujii T, Mochizuki T, Ishizaki H, Sata T
Department of Dermatology, Kanazawa Medical University, Ishikawa, Japan.
Pediatr Dermatol. 1998 Nov-Dec;15(6):456-8. doi: 10.1046/j.1525-1470.1998.1998015456.x.
A case of measles in a 26-year-old Japanese man is reported. A skin specimen taken on the third eruptive day from a maculopapular eruption on his chest was immunohistopathologically and electron microscopically examined using a rabbit polyclonal antibody against the nucleocapsid protein of the measles virus. The measles virus antigen was found in the inner cells of the acrosyringium and hair follicles. The measles virus nucleocapsid was electron microscopically identified in the nuclei of the inner cells of the acrosyringium. The findings suggest that the sweat from skin lesions might contain the measles virus.
报告了一例26岁日本男性的麻疹病例。在出疹第三天,从其胸部斑丘疹皮损处采集皮肤标本,使用抗麻疹病毒核衣壳蛋白的兔多克隆抗体进行免疫组织病理学和电子显微镜检查。在汗腺导管和毛囊的内层细胞中发现了麻疹病毒抗原。在汗腺导管内层细胞的细胞核中通过电子显微镜鉴定出了麻疹病毒核衣壳。这些发现表明,皮肤病变处的汗液可能含有麻疹病毒。