Laxmi T R, Bindu P N, Raju T R, Meti B L
Department of Neurophysiology, National Institute of Mental Health and Neurosciences, P.B. 2900, Hosur Road, Bangalore-560 029, Karnataka, India.
Brain Res. 1999 Jan 16;816(1):245-8. doi: 10.1016/s0006-8993(98)01187-1.
The present study examined the effects of ibotenic acid lesions of the ventral subiculum (SUB) on the ability of rats to memorize a rewarded alternation test in a T-maze. Results indicated that rats with ibotenic acid lesions (IL) of the ventral subiculum were impaired in postoperative acquisition of the spatial discrimination task, making more errors than the vehicle treated and normal control rats. In addition, all rats, including the IL group of rats, were able to memorize an acquired spatial behaviour. These findings suggest that the SUB play an important role in spatial information processing in rats.
本研究考察了腹侧下托（SUB）的鹅膏蕈氨酸损伤对大鼠在T迷宫中记忆奖励交替试验能力的影响。结果表明，腹侧下托接受鹅膏蕈氨酸损伤（IL）的大鼠在术后获取空间辨别任务时受损，比接受赋形剂处理的大鼠和正常对照大鼠犯更多错误。此外，所有大鼠，包括IL组大鼠，都能够记住习得的空间行为。这些发现表明，下托在大鼠的空间信息处理中起重要作用。
