Mäkikyrö T, Sauvola A, Moring J, Veijola J, Nieminen P, Järvelin M R, Isohanni M
Department of Psychiatry, University of Oulu, Finland.
Fam Process. 1998 Fall;37(3):335-44. doi: 10.1111/j.1545-5300.1998.00335.x.
This study investigates the relationship between the family type (two-parent and 4 different single-parent types, mainly divorced) during childhood up to 14 years of age and adult hospital-treated psychiatric disorders in a sample from the unselected, general population Northern Finland 1966 Birth Cohort (N = 11,017). Up to the end of 1994, a total of 387 individuals (3.5%) had a hospital-treated psychiatric disorder, with 3.1% in two-parent families and 5.4% in single-parent families (p < .001). The single-parent family was not associated with the child's schizophrenia or other psychotic disorders. The adjusted odds ratios (OR) for personality disorders were highest among individuals without a father before the age of 14 years (OR 4.8), or at birth only (OR 4.0), or with a history of parental divorce (OR 2.8). Parental divorce was also associated with alcoholism (OR 3.7) and parental death with depressive disorders (OR 3.4). In conclusion, we found an elevated risk of hospital-treated nonpsychotic disorder among individuals from a single-parent family background. It is likely that a combination of the single-parent family and psychosocial and/or genetic risk may influence the development of these disorders.
本研究调查了1966年芬兰北部未经过筛选的普通人群出生队列(N = 11,017)中,14岁及以下儿童时期的家庭类型(双亲家庭和4种不同的单亲家庭类型,主要是离异家庭)与成年后需住院治疗的精神障碍之间的关系。截至1994年底,共有387人(3.5%)患有需住院治疗的精神障碍,其中双亲家庭为3.1%,单亲家庭为5.4%(p <.001)。单亲家庭与儿童的精神分裂症或其他精神障碍无关。在14岁之前没有父亲的个体中,人格障碍的调整后比值比(OR)最高(OR 4.8),或仅在出生时没有父亲的个体中(OR 4.0),或有父母离异史的个体中(OR 2.8)。父母离异也与酗酒有关(OR 3.7),父母死亡与抑郁症有关(OR 3.4)。总之,我们发现单亲家庭背景的个体中,需住院治疗的非精神性障碍风险升高。单亲家庭与心理社会和/或遗传风险的综合作用可能会影响这些障碍的发展。