Silberbauer K
Abteilung Innere Medizin des Krankenhauses, Barmherzigen Brüder, Eisenstadt.
Acta Med Austriaca. 1998;25(4-5):133-5.
Obesity is a well documented separate risk factor for metabolic and vascular diseases which may reduce life expectancy for overweight people. This is expected to create soon a major health economic problem in more or less all western countries because the numbers of morbidly obese people increase steadily. It is a type of visceral android fat deposition which bears a high risk to develop vascular remodelling processes causing coronary and cerebral artery disease with all its consequences. The various biochemical processes which may contribute to cause these vascular lesions in obesity are discussed by the author and the various resulting clinical findings are described. Further the chance is emphasized to reduce by weight reduction the risks of obesity since regression of vascular changes may result by an even moderate loss of weight.
肥胖是一个有充分文献记载的代谢和血管疾病的独立危险因素,可能会缩短超重人群的预期寿命。由于病态肥胖人群数量稳步增加,预计这将在几乎所有西方国家很快引发一个重大的健康经济问题。这是一种内脏型男性化脂肪沉积,极易引发血管重塑过程,进而导致冠状动脉和脑血管疾病及其所有后果。作者讨论了肥胖中可能导致这些血管病变的各种生化过程,并描述了由此产生的各种临床发现。此外,强调了通过减轻体重来降低肥胖风险的可能性,因为即使适度减轻体重也可能导致血管变化的消退。