Poirier Paul, Giles Thomas D, Bray George A, Hong Yuling, Stern Judith S, Pi-Sunyer F Xavier, Eckel Robert H
Quebec Heart and Lung Institute, Sainte-Foy, Canada.
Arterioscler Thromb Vasc Biol. 2006 May;26(5):968-76. doi: 10.1161/01.ATV.0000216787.85457.f3.
Obesity is becoming a global epidemic in both children and adults, and it is associated with numerous co-morbidities such as cardiovascular diseases (CVD), type 2 diabetes, hypertension, certain cancers, and sleep apnea/sleep-disordered breathing. In fact, is an independent risk factor for CVD and CVD risks have been also documented in obese children, and is associated with reduced life expectancy. A variety of adaptations/alterations in cardiac structure and function occur in the individual as adipose tissue accumulates in excess amount. As a whole, overweight/obesity predispose or is associated with numerous cardiac complications such as coronary heart disease, heart failure, and sudden death through its impact on the cardiovascular system.
肥胖正在成为儿童和成人中的一种全球流行病，它与许多合并症相关，如心血管疾病（CVD）、2型糖尿病、高血压、某些癌症以及睡眠呼吸暂停/睡眠呼吸紊乱。事实上，肥胖是心血管疾病的一个独立危险因素，肥胖儿童中也有心血管疾病风险的记录，并且与预期寿命缩短有关。随着脂肪组织过量积累，个体的心脏结构和功能会发生各种适应性变化/改变。总体而言，超重/肥胖通过对心血管系统的影响，易引发或与许多心脏并发症相关，如冠心病、心力衰竭和猝死。
