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瑞士高危人群莱姆病的纵向研究。

Longitudinal study of Lyme borreliosis in a high risk population in Switzerland.

作者信息

Zhioua E, Gern L, Aeschlimann A, Sauvain M J, Van der Linden S, Fahrer H

机构信息

Department of Parasitology, University of Neuchâtel, Switzerland.

出版信息

Parasite. 1998 Dec;5(4):383-6. doi: 10.1051/parasite/1998054383.

DOI:10.1051/parasite/1998054383
PMID:9879563
Abstract

Orienteers from all parts of Switzerland (n = 416) were included in a longitudinal study for Lyme borreliosis. In spring 1986, the seroprevalence was 28.1%. At the beginning of the study, 84.3% of orienteers reported a history of tick bite, and 3.8% reported a past history of Lyme borreliosis. During the first (spring 1986-autumn 1986), second (autumn 1986-spring 1987) and third (spring 1987-autumn 1987) period, rates of seroconversion were 0.6%, 2.7% and 2.1% respectively. During the first and second period, clinical incidence were 1.0% and 0.25% respectively. No active Lyme borreliosis was detected during the third period. Among orienteers who seroconverted during the study (n = 16), only two developed clinical symptoms. Hence, Borrelia burgdorferi infection is often asymptomatic.

摘要

来自瑞士各地的定向运动员(n = 416)被纳入一项莱姆病的纵向研究。1986年春季,血清阳性率为28.1%。在研究开始时,84.3%的定向运动员报告有蜱叮咬史,3.8%报告有莱姆病既往史。在第一个时期(1986年春季 - 1986年秋季)、第二个时期(1986年秋季 - 1987年春季)和第三个时期(1987年春季 - 1987年秋季),血清转化发生率分别为0.6%、2.7%和2.1%。在第一个和第二个时期,临床发病率分别为1.0%和0.25%。在第三个时期未检测到活动性莱姆病。在研究期间血清转化的定向运动员中(n = 16),只有两人出现临床症状。因此,伯氏疏螺旋体感染通常无症状。

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