Lee L C, Lee H Y, Lee Y H, Young Y C, Huang S C
Department of Obstetrics and Gynecology, Taipei Municipal Women and Children's Hospital, Taiwan.
J Formos Med Assoc. 1998 Dec;97(12):866-8.
Gastric cancer during pregnancy is very rare. We present the case of a 32-year-old woman, gravida 1 para 0, who suffered from advanced gastric cancer during pregnancy. Although the clinical symptoms of the tumor were evident early in the third trimester, the tumor was not diagnosed until 7 days postpartum, when it was too far advanced for curative resection. Only palliative procedures were carried out. The woman died of the cancer less than 3 months postpartum. Early diagnosis of this disease entity is often difficult and a poor prognosis invariably ensures, unless obstetricians maintain a high level of awareness. In pregnant patients with eccentric symptoms of the gastrointestinal tract that persist beyond the second trimester, further endoscopic evaluation should be considered. Occult blood in stool concomitant with elevated serum carcinoembryonic antigen concentration should be considered as an important indicator for thorough endoscopic investigation.
妊娠期间患胃癌极为罕见。我们报告一例32岁初产妇，孕期罹患进展期胃癌。尽管肿瘤临床症状在孕晚期早期就已明显，但直到产后7天才确诊，此时肿瘤已进展至无法行根治性切除。仅实施了姑息性手术。该名女性产后不到3个月死于癌症。除非产科医生保持高度警惕，否则这种疾病实体的早期诊断往往困难，且预后必然不佳。对于妊娠晚期仍持续存在胃肠道异常症状的孕妇，应考虑进一步行内镜评估。粪便潜血伴血清癌胚抗原浓度升高应被视为进行全面内镜检查的重要指标。
