Libermann I M, Brazzuna H, Rodríguez J, Capano A, Neumark J
Pflugers Arch. 1976 Sep 30;365(2-3):191-6. doi: 10.1007/BF01067018.
Plasma volume, hematocrit, protein and electrolyte concentrations in plasma were measured in control and water-deprived rats every three days after starting the experiment until the 15th day. Plasma volume variations, as related to body weight, suggest that water loss from plasma was proportional to total body water at three days and after 9 days of water deprivation. Greater plasma water than body water loss was found during the period between 3 and 9 days. Plasma protein and electrolyte variations suggest that during water deprivation there is a loss of protein, sodium and potassium from plasma, which is proportionally less than that of plasma water. Potassium, calcium and inorganic phosphorus were lost proportionally to plasma water. The variations in plasma volume changes were partially explained as due to variations in plasma protein and electrolyte concentrations.
在实验开始后，每隔三天对对照组和缺水大鼠的血浆容量、血细胞比容、血浆中的蛋白质和电解质浓度进行测量，直至第15天。与体重相关的血浆容量变化表明，在缺水三天和九天后，血浆中的水分流失与总体液量成正比。在缺水3至9天期间，发现血浆水分流失比身体水分流失更多。血浆蛋白质和电解质变化表明，在缺水期间，血浆中蛋白质、钠和钾有所流失，但其流失比例小于血浆水分。钾、钙和无机磷的流失与血浆水分成比例。血浆容量变化的部分原因可解释为血浆蛋白质和电解质浓度的变化。
