Leiblum S R, Aviv A, Hamer R
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Hum Reprod. 1998 Dec;13(12):3569-74. doi: 10.1093/humrep/13.12.3569.
After leaving in-vitro fertilization (IVF) treatment, both successful and unsuccessful women are generally lost to follow-up. In order to assess overall life satisfaction as well as marital and sexual adjustment after the completion of infertility treatment, three groups of women were studied: group 1 (n = 41), successful IVF women; group 2 (n = 16), unsuccessful IVF women who adopted; and group 3 (n = 18), unsuccessful IVF women who remained childless. All women who had completed a minimum of three IVF cycles between the years 1982 and 1993 were invited to participate in a 'life after infertility' follow-up study. Those who agreed were mailed a lengthy questionnaire which included questions about their reproductive history and infertility treatment, the impact of infertility on their marital and sexual relationship and their final thoughts about treatment. Four standardized questionnaires were also administered. Results revealed that women who became biological mothers through IVF were significantly more satisfied with their lives than women who were unsuccessful in IVF and remained childless (F = 8.62, P < 0.001). Childless women reported that infertility had exerted a significantly greater negative impact on their marriages than that reported by the other two groups. There were no significant differences, however, between the three groups on the standardized measures of marital and sexual satisfaction.
在接受体外受精(IVF)治疗后,无论治疗成功与否,女性通常都会失去后续随访。为了评估不孕治疗结束后的总体生活满意度以及婚姻和性方面的调适情况,对三组女性进行了研究:第一组(n = 41),IVF治疗成功的女性;第二组(n = 16),接受IVF治疗但未成功且已领养孩子的女性;第三组(n = 18),接受IVF治疗但未成功且仍未生育的女性。邀请了所有在1982年至1993年期间至少完成三个IVF周期的女性参与一项“不孕治疗后的生活”随访研究。同意参与的女性收到了一份冗长的问卷,其中包括关于她们的生殖史和不孕治疗情况、不孕对其婚姻和性关系的影响以及她们对治疗的最终想法等问题。还发放了四份标准化问卷。结果显示,通过IVF成为亲生母亲的女性对生活的满意度明显高于IVF治疗未成功且仍未生育的女性(F = 8.62,P < 0.001)。未生育的女性报告称,不孕对其婚姻产生的负面影响明显大于其他两组报告的情况。然而,在婚姻和性满意度的标准化测量方面,三组之间没有显著差异。