Kodjabachian L, Lemaire P
NIH, NICHD, Laboratory of Molecular Genetics, 9000 Rockville Pike, Bethesda, Maryland 20892, USA.
Curr Biol. 1998;8(25):R918-21. doi: 10.1016/s0960-9822(98)00009-8.
Regionalisation of the amphibian embryo is classically thought to involve induction by the Spemann organiser, itself induced by the Nieuwkoop centre. This model has now been extended to teleosts, with the identification of a gene that appears to define the zebrafish equivalent of the Nieuwkoop centre.
传统观点认为,两栖动物胚胎的区域化涉及由施佩曼组织者诱导,而施佩曼组织者本身又是由nieuwkoop中心诱导产生的。现在,随着一种基因的发现,这个模型已经扩展到硬骨鱼,该基因似乎定义了斑马鱼中相当于nieuwkoop中心的结构。