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聚合酶链反应检测在脑内斑块状结核瘤诊断中的应用

Utility of PCR assay in diagnosis of en-plaque tuberculoma of the brain.

作者信息

Singh K K, Nair M D, Radhakrishnan K, Tyagi J S

机构信息

Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

J Clin Microbiol. 1999 Feb;37(2):467-70. doi: 10.1128/JCM.37.2.467-470.1999.

Abstract

This is the first report of a case in which diagnosis of en-plaque tuberculoma on the basis of magnetic resonance imaging (MRI) findings was confirmed by a Mycobacterium tuberculosis complex-specific PCR assay of cerebrospinal fluid. The accuracy of the diagnosis was supported by good response to antitubercular drugs, which was shown by repeat MRI studies performed after treatment.

摘要

这是首例基于磁共振成像(MRI)结果诊断为斑块状结核瘤,后经脑脊液结核分枝杆菌复合群特异性PCR检测得以证实的病例报告。抗结核药物治疗反应良好,治疗后重复MRI检查结果也支持了诊断的准确性。

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