低补体血症性荨麻疹性血管炎：环磷酰胺-地塞米松冲击疗法成功治疗
Hypocomplementaemic urticarial vasculitis: successful treatment with cyclophosphamide-dexamethasone pulse therapy.
作者信息
Worm M, Muche M, Schulze P, Sterry W, Kolde G
机构信息
Department of Dermatology, Charité Clinic, Humboldt University, Schumannstr. 20-21, D-10117 Berlin, Germany.
出版信息
Br J Dermatol. 1998 Oct;139(4):704-7. doi: 10.1046/j.1365-2133.1998.02473.x.
Systemic hypocomplementaemic urticarial vasculitis unresponsive to several immunosuppressive and immunomodulatory drugs was seen in two women aged 43 and 45 years. Cyclophosphamide-dexamethasone pulse therapy was started in both patients and resulted in significant clinical improvement. The pulse treatment was well tolerated in both patients and no major adverse effects occurred. These cases indicate that cyclophosphamide-dexamethasone pulse therapy is efficient in the treatment of hypocomplementaemic urticarial vasculitis.
两名分别为43岁和45岁的女性患有对多种免疫抑制和免疫调节药物均无反应的系统性低补体血症性荨麻疹性血管炎。两名患者均开始接受环磷酰胺-地塞米松冲击疗法，临床症状得到显著改善。两名患者对冲击治疗耐受性良好，未出现重大不良反应。这些病例表明，环磷酰胺-地塞米松冲击疗法在治疗低补体血症性荨麻疹性血管炎方面是有效的。
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